One of the biggest questions folks usually have when talking about getting their bikes fitted with S&S couplers is how does it all fit in the case. Well we recently packed up a rather large (61cm) rando bike into it's case. The entire bike with front rack, 700c wheels, and full fenders went in without much fuss. Didn't even have to remove the fork from the frame. You will need a few basic tools for the job, but they will all easily fit in the case with the bike: An S&S pedal wrench/hook spanner tool, a set of allen keys and possibly a box wrench or two depending on what kind of hardware your bike uses, and a mini pump. All stuff you would probably carry with you on a long ride anyway.
So we're putting this up here as reference material (and even breaking from our usually format, so the pictures will be larger...). Usually there's one best way to pack up a bike. You follow the same sequence each time and it will always work. The first couple of times that you do it, it will be kind of a pain in the ass (just like learning any new thing). But after you do it a few times it'll be a lot easier, you probably wouldn't even need to refer to the pics.
We here at Bantam Bicyles are happy to share this information. We are also happy to put couplers into you bike, whether it be a new custom bike from us or retrofitting your existing bike. We love opening up the entire world as a possible place to travel with and on your bicycle.